张建国-中国科学院大学-UCAS
[中文]
[English]
招生信息
教育背景
工作经历
专利与奖励
出版信息
科研活动
基本信息
张建国 男 硕导 其他电子邮件： zhangjg@genomics.cn通信地址： 广东省深圳市盐田区洪安三街21号华大综合园7栋邮政编码： 518083
研究领域
2001年至今一直从事基因组学和生物信息学相关研究工作。早期主要从事动植物、微生物的基因组学研究。作为生物信息骨干参加了中国杂交水稻基因组计划，并荣获2003年度中国科学院杰出科技成就集体奖（11/18）(2003-02-02-208)。先后参与了家蚕、家鸡、第一个亚洲人、玉米、家猪等大型基因组研究计划，主持了西瓜基因组的组装和生物信息分析工作。2010年至今研究重点在遗传病基因组研究，基于遗传病临床样本和表型信息，以多组学平台和生物信息技术为主，致力于揭示遗传病的分子基础和生物标志物，促进遗传病的临床筛查、诊断、干预和治疗。开展的研究主要集中在出生缺陷、罕见病、脑病、孕期疾病以及生物信息分析工具与方法的开发。
招生信息
招生专业
0710Z1-基因组学0710J3-生物信息学
招生方向
遗传病基因组研究及其生物信息工具开发
教育背景
2005-09--2011-06 复旦大学 博士研究生1997-09--2001-06 南开大学 本科
工作经历
工作简历
2011-07~现在, 深圳华大生命科学研究院, 实验室负责人/临床科研总监2001-07~2005-08,北京华大基因研究中心, 项目负责人/部门副主管
社会兼职
2020-03-20-2022-12-31,安徽医科大学特聘副教授, 特聘副教授2018-09-13-2023-09-13,中国微循环学会-神经变性病专委会-阿尔茨海默病生物标志物学组副主任委员, 副主任委员2018-07-20-2023-07-20,西北大学兼职教授, 兼职教授
专利与奖励
奖励信息
（1）&nbsp深圳市高层次专业人才,&nbsp一等奖,&nbsp市地级,&nbsp2009（2）&nbsp中国科学院杰出科技成就奖,&nbsp部委级,&nbsp2004
专利成果
[1] 袁永一, 林琼芬, 戴朴, 管李萍, 高雪, 谌于蓝, 张建国. 基因突变体及其应用.&nbsp中国:&nbspCN110878306A,&nbsp2020-03-13.[2] 高雪, 袁永一, 戴朴, 林琼芬, 管李萍, 张建国, 谌于蓝. 基因突变体及其应用.&nbspCN:&nbspCN110878307A,&nbsp2020-03-13.[3] 戴兰兰, 杨勇, 张建国, 林志淼, 刘汉奎, 冯程, 谌于蓝, 汪慧君, 汪建. KLHL24基因突变体及其应用.&nbspCN:&nbspCN107974436B,&nbsp2019-11-08.[4] 何思捷, 张建国, 刘轩竹, 李建康, 徐讯. VPS13B基因突变体及其应用.&nbspCN:&nbspCN105779463B,&nbsp2019-08-09.[5] 布娟, 何思捷, 张建国, 方明艳, 王乐今, 刘敬. EPHA2基因突变型及其应用.&nbspCN:&nbspCN106167800B,&nbsp2019-07-19.[6] 高雪, 戴朴, 袁永一, 林琼芬, 管李萍, 张建国, 党孝. 分离的编码IFNLR1突变体的核酸及其应用.&nbspCN:&nbspCN109943569A,&nbsp2019-06-28.[7] 廖卫平, 周青, 石奕武, 管李萍, 秦兵, 何娜, 张建国. 遗传性癫痫伴热性惊厥附加症SCN1A基因新突变.&nbsp中国:&nbspCN104774841B,&nbsp2018-08-31.
出版信息
发表论文
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科研活动
科研项目
（ 1 ）&nbsp基于多组学方法的帕金森病发病机制研究, 主持, 省级, 2019-03--2022-03（ 2 ）&nbsp遗传和环境因素交互作用下神经环路的沉默与早期AD发病, 参与, 国家级, 2016-07--2021-06（ 3 ）&nbsp阿尔茨海默病遗传机制及生物标记技术的研发, 主持, 省级, 2015-08--2017-08（ 4 ）&nbsp眼科出生缺陷及遗传性疾病家系收集与珍惜资源复制, 主持, 国家级, 2014-05--2017-04（ 5 ）&nbspHBV感染相关疾病基因组医学标记物研究, 参与, 国家级, 2014-04--2017-04（ 6 ）&nbsp眼科单基因病致病基因发现研究及检测技术开发, 主持, 省级, 2013-08--2015-07（ 7 ）&nbsp西瓜基因组测序及生物信息学分析, 主持, 国家级, 2010-01--2011-12
参与会议
（1）基因组时代的眼科临床与科研 中国研究型医院学会眼科学会与视觉科学专委会2019学术年会 2019-03-22
2013 中国科学院大学，网络信息中心.